Categorie
Oxaloplatino [Spanish]
Les marques,
Oxaloplatino [Spanish]
Analogs
Oxaloplatino [Spanish]
Les marques melange
No information avaliable
Oxaloplatino [Spanish]
Formule chimique
C8H12N2O4Pt
Oxaloplatino [Spanish]
RX lien
http://www.rxlist.com/cgi/generic/eloxatin.htm
Oxaloplatino [Spanish]
FDA fiche
Oxaloplatino [Spanish]
msds (fiche de securite des materiaux)
Oxaloplatino [Spanish]
Synthese de reference
Aucune information disponible
Oxaloplatino [Spanish]
Poids moleculaire
395.27 g/mol
Oxaloplatino [Spanish]
Point de fusion
No information avaliable
Oxaloplatino [Spanish]
H2O Solubilite
Aucune information disponible
Oxaloplatino [Spanish]
Etat
Solid
Oxaloplatino [Spanish]
LogP
No information avaliable
Oxaloplatino [Spanish]
Formes pharmaceutiques
Aucune information disponible
Oxaloplatino [Spanish]
Indication
Pour le traitement des tumeurs malignes du côlon, du rectum, et de l'ovaire
Oxaloplatino [Spanish]
Pharmacologie
L'oxaliplatine inhibe sélectivement la synthèse de l'acide désoxyribonucléique (ADN). Le contenu guanine et la cytosine est corrélée avec le degré d'oxaliplatine induit une réticulation. A des concentrations élevées de la drogue, de l'ARN cellulaire et la synthèse des protéines sont également supprimées.
Oxaloplatino [Spanish]
Absorption
Aucune information disponible
Oxaloplatino [Spanish]
Toxicite
Aucune information disponible
Oxaloplatino [Spanish]
Information pour les patients
Patients and patientsí caregivers should be informed of the expected side effects of ELOXATIN, particularly
its neurologic effects, both the acute, reversible effects, and the persistent neurosensory toxicity. Patients should
be informed that the acute neurosensory toxicity may be precipitated or exacerbated by exposure to cold or cold
objects. Patients should be instructed to avoid cold drinks, use of ice, and should cover exposed skin prior to
exposure to cold temperature or cold objects.
Patients must be adequately informed of the risk of low blood cell counts and instructed to contact their
physician immediately should fever, particularly if associated with persistent diarrhea, or evidence of infection
develop.
Patients should be instructed to contact their physician if persistent vomiting, diarrhea, signs of dehydration,
cough or breathing difficulties occur, or signs of allergic reaction appear.
Oxaloplatino [Spanish]
Organismes affectes
Les humains et autres mammifères